CVE Research Seminar

The CVE Research Seminar is a forum for scientific exchange in the group of Cardiovascular Engineering of the ARTORG Center. The CVE Research Seminar convenes at least once per month (typically on Thursdays at 16:00 in F502 of the ARTORG building at Murtenstrasse 50). There are invited talks by external speakers, discussions of papers (journal club) as well as internal presentations of research projects. The CVE Research Seminar is open to guests.

Next Event

A fluid-structure interaction approach for the simulation of biological flows.

Prof. Marco D. de Tullio

Department of Mechanics, Mathematics and Management

Politecnico di Bari, Italy

10:00-11:00,  December 18th, 2018

Murtenstrasse 50, 3008 Bern, Floor F, Room F502

 

 

Abstract:

Fluid-structure interaction (FSI) problems are found in many engineering areas and their computational modeling is particularly challenging. Among different FSI problems, biological applications are becoming of ever increasing interest in the scientific community. In such cases, describing the dynamics of the interaction between the body and the fluid is not a trivial task, since the numerical method needs to be able to handle in an efficient way complex and very thin geometries undergoing large deformations, while preserving accuracy.

In this seminar, a versatile numerical method is presented to predict the fluid-structure interaction of bodies with arbitrary thickness immersed in an incompressible fluid, with the aim of simulating different biological engineering applications. A direct-forcing immersed boundary method is adopted, based on a moving-least-squares approach to reconstruct the solution in the vicinity of the immersed surface. A simple spring-network model is considered for describing the dynamics of deformable structures, so as to easily model and simulate different biological systems that not always may be described by simple continuum models, without affecting the computational time and simplicity of the overall method. The fluid and structures are coupled in a strong way, in order to avoid instabilities related to large accelerations of the bodies. The effectiveness of the method is validated by means of several test cases involving: rigid bodies, infinitely thin elastic structures with mass, flapping flags, with a very good agreement with available experimental data and numerical results obtained by different methods.

The blood dynamics through artificial heart valves is selected as a case study. Realistic geometries for three valves (bi- and tri-leaflet mechanical, bio-prosthetic) and ascending aorta are considered under pulsatile flow conditions. The numerical tool presented is able to reproduce accurately the flow and structure dynamics, giving results in good agreement with experimental data obtained for similar configurations. Blood damage is estimated by means of a high-fidelity hemolysis model, based on a coarse-grained description of the erythrocyte membrane spectrin cytoskeleton. Finally, the first results of a fluid-structure-electrophysiology interaction model are presented. The numerical tool is put to good effect simulating the whole left heart, including atrium, aorta and ventricle with aortic/mitral valves.

Date/Time Speaker Title Location
 18.12.2018
10:00-11:00

Prof. Marco D. de Tullio, Department of Mechanics, Mathematics and Management, Politecnico di Bari

A fluid-structure interaction approach for the simulation of biological flows. Murtenstrasse 50, 3008 Bern, Floor F, Room F502
23.11.2018 11:15-12:00 Prof. Dr. med. Andreas Harloff, Klinik für Neurologie und Neurophysiologie, Universitätsklinikum Freiburg Charakterisierung der Aorta und des Herzens mittels 4D Fluss MRT – Daten einer Populationsstudie Room «Paradiso» H612, Wirtschaftsgebäude, Inselspital Bern
22.02.2018
16:00-17:00
Mr. Ali Mosayyebi Accumulation of stent encrustations depends on fluid dynamics: In-vitro study on a stent-on-a-chip model  Murtenstrasse 50, 3008 Bern, Floor F, Room F502
23.112017
14:00-15:00
Utku Gülan, Institute of Environmental Engineering, ETH Zürich Assessment of Energy Loss in the Ascending Aorta of Patients with Stenosis Murtenstrasse 50, 3008 Bern, Floor F, Room F502
28.09.2017
16:00-17:00
Dimosthenis Pasadakis, Università della Svizzera Italiana, Lugano  Fluid-Structure Interaction Simulations of the Human Heart Murtenstrasse 50, 3008 Bern, Floor F, Room F502
 08.06.2017
16:00-17:00
Lena Wiegmann, University of Zurich
Blood damage in ventricular assist devices Murtenstrasse 50, 3008 Bern, Floor F, Room F502
01.06.2017
15:30-16:30
Dario De Marinis, Politecnico di Bari Fluid-Structure-Interaction Immersed-Boundary Methods for Multiphysics Murtenstrasse 50, 3008 Bern, Floor F, Room F502
1.12.2016
16:00-17:00
Christoph Brücker, City University London  Strömungsforschung an biomedizinischen Fragestellungen: Ein Überblick  Murtenstrasse 50, 3008 Bern, Floor F, Room F502
13.10.2016
16:00-17:00
Timo Koch, Universität Stuttgart  An embedded multidimensional model for flow and transport processes in vascularized biological tissue  Murtenstrasse 50, 3008 Bern, Floor F, Room F502
12.09.2016
17:15-18:00
Marcel Filoche, Ecole Polytechnique, Paris 
Fluid transport and surfactant delivery into the lung airway system 
Inselspital, Polikliniktrakt 2 Kursraum D 517
10.06.2016
16:00-17:00
Marco Castagna, Politecnico di Milano A mock circulation loop for the right heart
Murtenstrasse 50, 3008 Bern, Floor F, Room F502
19.05.2016
16:00-17:00 
Alberto Mantegazza, Politecnico di Milano Finite element computational model for the design of a polymeric tracheal stent implantable in biological prosthesis
Murtenstrasse 50, 3008 Bern, Floor A, Room A008
28.04.2016
15:00-16:00
Gian-Reto Nussbaumer, ARTORG Center, University of Bern Minimally invasive measurement of flow rate and blood pressure in the portal vein with an inflatable cuff Murtenstrasse 50, 3008 Bern, Floor A, Room A008
21.04.2016
16:00-17:00
Lino Widmer, ARTORG Center, University of Bern Blood flow measurement in the cerebral microcirculation with the double-circle method  Murtenstrasse 50, 3008 Bern, Floor F, Room F502