2022/02/16 | People | Biomechanics
PhD thesis defense Denis Schenk
Congratulations to Denis Elia Schenk, who successfully defended his PhD project “Personalized Homogenized Finite Element Analysis for the Reproducible Assessment of Bone Strength” on 11 February 2022! For his research at the Musculoskeletal Biomechanics (MSB) lab, Denis has worked on methods to assess bone strength, especially in view of osteoporosis risk. His research has won the Best Student Award at the 17th Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) Symposium 2021.
The prediction of personalized in vivo bone strength from HR-pQCT in a nutshell: 1) high resolution CT of patients bone segment, 2) basic image processing and segmentation of VOI, 3) generation of homogenized finite element model including 2-phase material mapping and computation fabric orientation and 4) simulation of bone strength and validation with experimental results.
Publications:
- Reference values and clinical predictors of bone strength for HR-pQCT-based distal radius and tibia strength assessments in women and men, Osteoporos. Int. 31, 1913–1923 (2020)
- In vivo repeatability of homogenized finite element analysis based on multiple HR-pQCT sections for assessment of distal radius and tibia strength, Bone, Volume 141, December 2020.
- Fabric-Elasticity Relationships of Tibial Trabecular bone are Similar in Osteogenesis Imperfecta and Healthy Individuals, Bone, Volume 155, February 2022.
- Unified validation of a refined HR-pQCT based homogenized finite element method to predict strength of the distal segments in radius and tibia, JMBBM, Nov. 2021 (under review).
