2022/06/24 | People | Biomechanics

PhD thesis defense Michael Indermaur

Congratulations to Michael Indermaur, who successfully defended his PhD project “Osteogenesis Imperfecta does not compromise the micromechanical properties of human bone extracellular matrix” on 1 June! For his research at the Musculoskeletal Biomechanics (MSB) lab in collaboration with EMPA and McGill university, Michael measured the mechanical properties of bones with “brittle bone disease” (Osteogenesis Imperfecta) at the extracellular matrix level to find out more about this rare genetic, inherited, collagen-related bone disease. With his first PhD publication “Compressive Strength of Iliac Bone ECM Is Not Reduced in Osteogenesis Imperfecta and Increases with Mineralization”, Michael has won the Best Preclinical Publication Award 2022 of the Swiss Bone and Mineral Society (SBMS).

Compressive bone strength of dry OI bone ECM is dominated by the extent of mineralisation.