The Computational Bioengineering Group (CBE) develops computational models to address clinical challenges in ophthalmology and orthopedics. We combine clinical imaging with ex vivo and in vivo experimental data to build accurate, physics-based representations of patient-specific tissue biomechanics. A key focus of our work is the development and validation of non-invasive methods to obtain biomechanical data in vivo, supporting the creation of digital twins that reflect individual patient conditions. This integrative approach advances understanding of disease mechanisms, enables treatment simulation, and contributes to more personalized therapies
