Musculoskeletal biomechanics (MSB) is mechanics applied to the locomotor apparatus and studies motion, forces, equilibrium, energy and the material behaviour of skeletal tissues and muscles from the extracellular matrix level up to the whole-body scale. MSB plays a critical role in understanding disease pathophysiology, for instance in osteoporosis, osteoarthritis, intervertebral disc degeneration or sarcopenia where the cellular response to altered loading mechanisms contribute to disease initiation and progression. MSB enables translation of laboratory discoveries into clinical practice through collaboration between biomedical engineers and clinicians, leading to improved patient treatment and outcomes.
